Urological System Drugs
alpha ketoanalogue tablet
Regulation of Blood System
ISO,GMP FDA CGMP:
Alpha Ketoanalogue Tablet
This product contains all amino acids essential for uremic patients, five out of them are keto or hydroxyanalogue in the form of calcium salts. Therefore it allows reduction in the nitrogen supply and provides calcium. It is a medication for the treatment of chronic kidney disease patients on conservative management therapy (CKD stage I, II, III). In combination with very low protein diet / low protein diet, it helps in delaying the progression of kidney disease in the predialysis period.
One film-coated tablet contains :
Calcium-3-methyl-2-oxovalerate (a-ketoanalogue of isoleucine, Calcium salt)67 mg
Calcium-4-methyl-2-oxovalerate (a-ketoanalogue of leucine, Calcium-salt)101 mg
101 mg Calcium-2-oxo-3-phenylpropionate (a-ketoanalogue of phenylalanine, Calcium-salt) 68 mg
Calcium-3-methyl-2-oxobutyrate (a-ketoanalogue of valine, Calcium-salt) 86 mg
Calcium-DL-2-hydroxy-4-(methylthio)-butyrate a-hydro xyanalogue of methionine, Calcium salt) 59 mg
L-lysine 105 mg L-threonine 53 mg L-tryptophan 23 mg L-histidine 38 mg L-tyrosine 30 mg
Prevention and therapy of damages due to faulty or deficient protein metabolism in chronic renal insufficiency in connection with limited protein in food of 40 g per day (for adults) and less; i.e. generally in patients with a glomerular filtration rate (GFR) below 25 ml/min.
Hypercalcaemia, disturbed amino acid metabolism. In case of hereditary phenylketonurie it has to be taken into account that this product contains phenylalanine.